[D-Trp8]-?-MSH

• Target:

  Melanocortin Receptor

• Related Pathways:

  GPCR/G Protein|||Neuroscience

• Bioactivity:

  [D-Trp8]-?-MSH is a selective melanocortin 3 (MC3) receptor agonist with IC50 values of 6.7, 340, and 600 nM for human MC3, MC5, and MC4 receptors, respectively. [D-Trp8]-?-MSH also exhibits anti-inflammatory efficacy.

• Smiles:

  C([C@@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@H](CC2=CN=CN2)NC(CNC([C@@H](NC([C@@H](NC([C@H](CC3=CC=C(O)C=C3)N)=O)C(C)C)=O)CCSC)=O)=O)=O)=O)CCCNC(=N)N)=O)C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(NCC(O)=O)=O)=O)CCCNC(=N)N)=O)CC(O)=O)=O)C=5C=6C(NC5)=CC=CC6

• Molecular Formula:

  C74H99N21O16S

• Molecular Weight:

  1570.79

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  321351-81-9