γ1-MSH

• Target:

  Melanocortin Receptor

• Related Pathways:

  Neuroscience|||GPCR/G Protein

• Bioactivity:

  Endogenous melanocortin MC3 receptor agonist (pKi = 7.46) that displays ~ 40-fold selectivity over MC4. Increases the release of extracellular dopamine, which induces grooming and vertical activity (rearing) in rats. Exhibits hypertensive, tachycardic and short-term analgesic activity in vivo.

• Smiles:

  C ([C@H] (NC ([C@@H] (NC ([C@H] (CC1=CC=CC=C1) NC ([C@H] (CC2=CN=CN2) NC (CNC ([C@@H] (NC ([C@@H] (NC ([C@H] (CC3=CC=C (O) C=C3) N) =O) [C@@H] (C) C) =O) CCSC) =O) =O) =O) =O) CCCNC (=N) N) =O) C (N[C@H] (C (N[C@H] (C (N[C@@H] (CC4=CC=CC=C4) C (N) =O) =O) CCCNC (=N) N) =O) CC (O) =O) =O) C=5C=6C (NC5) =CC=CC6

• Molecular Formula:

  C72H97N21O14S

• Molecular Weight:

  1512.76

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  72629-65-3