HSDVHK-NH2

• Target:

  Integrin

• Related Pathways:

  Cytoskeletal Signaling

• Bioactivity:

  Potent antagonist of the integrin ?v?3-vitronectin interaction (IC50 = 25.72 nM) . Blocks proliferation and induces apoptosis in HUVECs; antiangiogenic.

• Smiles:

  CC(C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1c[nH]cn1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCCCN)C(N)=O

• Molecular Formula:

  C30H48N12O9

• Molecular Weight:

  720.78

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  848644-86-0