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Iprodione

CAT: 0804-HY-B1978-01Size: 250 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1978-01Size:250 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Iprodione is an orally active diformimide fungicide. Iprodione can specifically cause oxidative damage by producing free radicals (ROS) . Iprodione is also an antiandrogen agent that delays adolescent development in rats and reduces sexual behavior and reproductive ability in rats[1][2][3][4][5].
CAS Number
36734-19-7
UNSPSC
12352005
Hazard Statement
H351
Target
Androgen Receptor; Fungal; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/iprodione.html
Purity
99.25
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N(C(N1C2=CC(Cl)=CC(Cl)=C2)=O)CC1=O)NC(C)C
Molecular Formula
C13H13Cl2N3O3
Molecular Weight
330.17
Precautions
H351
References & Citations
[1]Reilly C C, et al. The Effects of the Fungicide, Iprodione, on the Mycelium of Sclerotinia sclerotiorum[J]. Phytopathology, 1981, 71 (7) : 722-727.|[2]Griffiths RG, et al. Lipid composition of Botrytis cinerea and inhibition of its radiolabelling by the fungicide iprodione. New Phytol. 2003 Oct;160 (1) :199-207. |[3]Radice S, et al. Effect of iprodione, a dicarboximide fungicide, on primary cultured rainbow trout (Oncorhynchus mykiss) hepatocytes. Aquat Toxicol. 2001 Sep;54 (1-2) :51-8. |[4]Abd-Elhakim Y M, et al. Iprodione and Chlorpyrifos, Alone and in a Mixture, Impaired Male Fertility and Sexual Behavior in Adult Rats via Suppression of Steroidogenic Genes and SIRT1/TERT/PGC-1α Pathway[J]. 2021.|[5]Blystone CR, et al. Iprodione delays male rat pubertal development, reduces serum testosterone levels, and decreases ex vivo testicular testosterone production. Toxicol Lett. 2007 Nov 1;174 (1-3) :74-81.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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