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Macluraxanthone

CAT: 0931-TN5912-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-TN5912-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
5848-14-6
Target
Antioxidant, TNF
Related Pathways
Oxidation-Reduction, Apoptosis
Bioactivity
Macluraxanthone (3-Hydroxyblancoxanthone) has many biological activities including anticholinesterase, antioxidant, anticancer, antimalarial, anti-inflammatory and immunomodulatory effects. macluraxanthone promotes the polarization of M1-like pro-inflammatory macrophages by increasing the percentage of macrophages expressing CD86 while decreasing their expression of CD14, CD11b and CD80. Macluraxanthone significantly reduced the production of TNF-α and IL-10 cytokines in the presence of the pro-inflammatory stimulant lipopolysaccharide.
Smiles
O=C1C2=CC=C(O)C(O)=C2OC=3C1=C(O)C=4C=CC(OC4C3C(C=C)(C)C)(C)C
Molecular Formula
C23H22O6
Molecular Weight
394.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
MBS5788013Macluraxanthone

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