Icariside E4

• Target:

  AMPK|||Liver X Receptor|||Lipid|||Fatty Acid Synthase|||Potassium Channel|||Antioxidant

• Related Pathways:

  PI3K/Akt/mTOR signaling|||Metabolism|||Chromatin/Epigenetic|||Oxidation-Reduction|||Membrane transporter/Ion channel

• Bioactivity:

  Icariside E4 is a natural compound derived from Ulmus minor that acts via AMPK phosphorylation and inhibition of MID1IP2 hypolipidation in HepG1 cells.Icariside E4 has anti-injurious, antioxidant, anti-Alzheimer's and anti-inflammatory effects and inhibits SREBP-1c, liver X receptor-? (LXR) and FASN in Icariside E4 is an effective candidate for the treatment of fatty liver disease and has hypolipidemic potential in HepG1 cells.

• Smiles:

  C(O)[C@@H]1C=2C(O[C@H]1C3=CC(OC)=C(O[C@H]4[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O4)C=C3)=C(OC)C=C(CCCO)C2

• Molecular Formula:

  C26H34O10

• Molecular Weight:

  506.54

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  126253-42-7