Icariside D2

• Target :

  Angiotensin-converting Enzyme (ACE) |||Akt|||Apoptosis|||HIV Protease

• Related Pathways :

  Microbiology/Virology|||Cytoskeletal Signaling|||PI3K/Akt/mTOR signaling|||Proteases/Proteasome|||Apoptosis|||Metabolism

• Bioactivity :

  Icariside D2 shows significant cytotoxic activity on the HL-60 cell line with the IC50 value of 9.0 ± 1.0 uM, it induces apoptosis via alteration of expression of apoptosis-related proteins and decreased phosphorylation of AKT in HL-60 cells.

• Smiles :

  OCCc1ccc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1

• Molecular Formula :

  C14H20O7

• Molecular Weight :

  300.3

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  38954-02-8