Dehydroglyasperin C

• Target :

  TNF|||Nrf2|||PI3K|||DNA/RNA Synthesis|||JNK|||COX|||Autophagy|||ERK|||p38 MAPK|||NADPH|||I?B/IKK|||NF-?B|||Akt

• Related Pathways :

  Apoptosis|||Cytoskeletal Signaling|||Autophagy|||MAPK|||Neuroscience|||PI3K/Akt/mTOR signaling|||DNA Damage/DNA Repair|||Cell Cycle/Checkpoint|||Metabolism|||NF-?B|||Immunology/Inflammation

• Bioactivity :

  Dehydroglyasperin C is a potent NAD (P) H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C possesses potent antioxidant, cancer chemopreventive, and neuroprotective activities, it has protective effects against chronic diseases caused by reactive oxygen species as well as potential as an antioxidant food additive. Dehydroglyasperin C protects neuronal cells against glutamate-induced oxidative injury through the induction of HO-1 expression, which is, in turn, activated maybe through Nrf2-Keap1 and PI3K/AKT signaling pathways.

• Smiles :

  COc1c(CC=C(C)C)c(O)cc2OCC(=Cc12)c1ccc(O)cc1O

• Molecular Formula :

  C21H22O5

• Molecular Weight :

  354.4

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  199331-35-6