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Dehydroglyasperin C

CAT: 0931-TN3806Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-TN3806Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
199331-35-6
Target
TNF, Nrf2, PI3K, DNA/RNA Synthesis, JNK, COX, Autophagy, ERK, p38 MAPK, NADPH, IκB/IKK, NF-κB, Akt
Related Pathways
Apoptosis, Cytoskeletal Signaling, Autophagy, MAPK, Neuroscience, PI3K/Akt/mTOR signaling, DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Metabolism, NF-κB, Immunology/Inflammation
Bioactivity
Dehydroglyasperin C is a potent NAD (P) H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C possesses potent antioxidant, cancer chemopreventive, and neuroprotective activities, it has protective effects against chronic diseases caused by reactive oxygen species as well as potential as an antioxidant food additive. Dehydroglyasperin C protects neuronal cells against glutamate-induced oxidative injury through the induction of HO-1 expression, which is, in turn, activated maybe through Nrf2-Keap1 and PI3K/AKT signaling pathways.
Smiles
COc1c(CC=C(C)C)c(O)cc2OCC(=Cc12)c1ccc(O)cc1O
Molecular Formula
C21H22O5
Molecular Weight
354.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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