Dehydroglyasperin D

• CAS Number :

  517885-72-2

• Target :

  P38 MAPK|||Reductase|||Akt|||Prostaglandin Receptor|||GSK-3|||JNK|||COX|||PI3K|||DNA/RNA Synthesis|||ROS

• Related Pathways :

  DNA Damage/DNA Repair|||PI3K/Akt/mTOR signaling|||Cell Cycle/Checkpoint|||Endocrinology/Hormones|||GPCR/G Protein|||Metabolism|||Neuroscience|||Immunology/Inflammation|||Cytoskeletal Signaling|||Stem Cells|||MAPK

• Bioactivity :

  Dehydroglyasperin D exhibits anticancer, anti-inflammatory, anti-obesity, antioxidant and anti-aldose reductase effects, it inhibits the proliferation of HT-29 human colorectal cancer cells through direct interaction with phosphatidylinositol 3-kinase; it also mediates suppression of both COX-2 expression and the MLK3 signalling pathway through direct binding and inhibition of MLK3. Dehydroglyasperin D shows strong ferric reducing activities and effectively scavenged DPPH, ABTS (+), and singlet oxygen radicals.

• Smiles :

  O(C)C1=C2C(=CC(OC)=C1CC=C(C)C)OCC(=C2)C3=C(O)C=C(O)C=C3

• Molecular Formula :

  C22H24O5

• Molecular Weight :

  368.42

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C