Coronarin D

• Target:

  Bcl-2 Family|||c-Myc|||NF-?B|||Caspase|||Antifection|||COX|||TNF

• Related Pathways:

  Microbiology/Virology|||Proteases/Proteasome|||Apoptosis|||Immunology/Inflammation|||Cell Cycle/Checkpoint|||Neuroscience|||NF-?B

• Bioactivity:

  Coronarin D shows promising antifungal activity against C. albicans in vitro, the minimum inhibitory concentration (MIC) and the minimum fungicidal concentration (MFC) were 2 and 4 mg/mL, respectively; it is active against tested Gram-positive bacteria, inactive for tested Gram-negative bacteria, and weakly active against tested fungi; using coronarin D-antibiotic drug combination can combat the infectious diseases.Coronarin D inhibits NF-kappaB activation pathway, which leads to inhibition of inflammation, invasion, and osteoclastogenesis, as well as potentiation of apoptosis.

• Smiles:

  CC1(C)CCCC2(C)C(CC=C3CC(O)OC3=O)C(=C)CCC12|w:10.9|

• Molecular Formula:

  C20H30O3

• Molecular Weight:

  318.457

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  119188-37-3