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Coronarin D

CAT: 931-TN3708Size: 5 mgDry Ice: NoHazardous: No
5 mgSelected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
119188-37-3
Target
Bcl-2 Family|||c-Myc|||NF-?B|||Caspase|||Antifection|||COX|||TNF
Related Pathways
Microbiology/Virology|||Proteases/Proteasome|||Apoptosis|||Immunology/Inflammation|||Cell Cycle/Checkpoint|||Neuroscience|||NF-?B
Bioactivity
Coronarin D shows promising antifungal activity against C. albicans in vitro, the minimum inhibitory concentration (MIC) and the minimum fungicidal concentration (MFC) were 2 and 4 mg/mL, respectively; it is active against tested Gram-positive bacteria, inactive for tested Gram-negative bacteria, and weakly active against tested fungi; using coronarin D-antibiotic drug combination can combat the infectious diseases.Coronarin D inhibits NF-kappaB activation pathway, which leads to inhibition of inflammation, invasion, and osteoclastogenesis, as well as potentiation of apoptosis.
Smiles
CC1(C)CCCC2(C)C(CC=C3CC(O)OC3=O)C(=C)CCC12|w:10.9|
Molecular Formula
C20H30O3
Molecular Weight
318.457
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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