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Coronarin D

CAT: 0931-TN3708Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-TN3708Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
119188-37-3
Target
Bcl-2 Family, c-Myc, NF-κB, Caspase, Antifection, COX, TNF
Related Pathways
Microbiology/Virology, Proteases/Proteasome, Apoptosis, Immunology/Inflammation, Cell Cycle/Checkpoint, Neuroscience, NF-κB
Bioactivity
Coronarin D shows promising antifungal activity against C. albicans in vitro, the minimum inhibitory concentration (MIC) and the minimum fungicidal concentration (MFC) were 2 and 4 mg/mL, respectively; it is active against tested Gram-positive bacteria, inactive for tested Gram-negative bacteria, and weakly active against tested fungi; using coronarin D-antibiotic drug combination can combat the infectious diseases.Coronarin D inhibits NF-kappaB activation pathway, which leads to inhibition of inflammation, invasion, and osteoclastogenesis, as well as potentiation of apoptosis.
Smiles
CC1(C)CCCC2(C)C(CC=C3CC(O)OC3=O)C(=C)CCC12 |w:10.9|
Molecular Formula
C20H30O3
Molecular Weight
318.457
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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