Coronarin A

• Target :

  MTOR|||S6 Kinase

• Related Pathways :

  PI3K/Akt/mTOR signaling|||MAPK

• Bioactivity :

  Coronarin, A, B, C, and D are cytotoxic prinicples from the rhizomes of Hedychium coronarium, Zingiberaceae. Coronarin A exhibits good growth inhibition activities on HUVEC proliferation, it effectively suppresses the growth factor induced tube formation of HUVEC at the concentration of 10 microg/mL. Coronarin A has anti-inflammatory activity, it exhibits potent inhibition (IC50 <6.1708g/mL) against fMLP-induced superoxide production and elastase release.

• Smiles :

  CC1(C)CCC[C@@]2(C)[C@H]1C[C@H](O)C(=C)[C@@H]2\C=C\c1ccoc1

• Molecular Formula :

  C20H28O2

• Molecular Weight :

  300.44

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  119188-33-9