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Aflatrem

CAT: 0931-TN3351Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-TN3351Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
70553-75-2
Target
GABA Receptor
Related Pathways
Membrane transporter/Ion channel, Neuroscience
Bioactivity
Aflatrem is a tremorgenic mycotoxin with acute neurotoxic effects, a single low dose of aflatrem is able to induce degeneration of neuronal processes in hippocampal neurotransmitter systems. Aflatrem potentiates the gamma-aminobutyric acid (GABA) -induced chloride current, the potentiating action of aflatrem on the GABAA receptor channel may explain the initial symptoms of intoxication caused by aflatrem in vivo.
Smiles
CC(C)(C=C)c1cccc2[nH]c3c(CC4CCC5(O)C6=CC(=O)C7OC6(CCC5(C)C34C)OC7(C)C)c12 |t:19|
Molecular Formula
C32H39NO4
Molecular Weight
501.667
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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MBS5787717beta-Aflatrem

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