Withanolide B

• Target :

  Wnt/beta-catenin|||PARP|||ERK

• Related Pathways :

  Stem Cells|||MAPK|||Cytoskeletal Signaling|||Chromatin/Epigenetic|||DNA Damage/DNA Repair

• Bioactivity :

  Withanolide B, a natural product isolated from Withania somnifera Dunal, promotes osteogenic differentiation of human bone marrow-derived mesenchymal stem cells (hBMSCs) via the ERK1/2 and Wnt/?-catenin signalling pathways, thereby enhancing bone healing. Withanolide B exhibits affinity for the catalytic domain of PARP-1.

• Smiles :

  [H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@@H]4O[C@@H]4[C@@]4(O)CC=CC(=O)[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)[C@@]1([H])CC(C)=C(C)C(=O)O1

• Molecular Formula :

  C28H38O5

• Molecular Weight :

  454.6

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  56973-41-2