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Withanolide B

CAT: 0931-TN2310-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TN2310-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
56973-41-2
Target
Wnt/beta-catenin, PARP, ERK
Related Pathways
Stem Cells, MAPK, Cytoskeletal Signaling, Chromatin/Epigenetic, DNA Damage/DNA Repair
Bioactivity
Withanolide B, a natural product isolated from Withania somnifera Dunal, promotes osteogenic differentiation of human bone marrow-derived mesenchymal stem cells (hBMSCs) via the ERK1/2 and Wnt/β-catenin signalling pathways, thereby enhancing bone healing. Withanolide B exhibits affinity for the catalytic domain of PARP-1.
Smiles
[H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@@H]4O[C@@H]4[C@@]4(O)CC=CC(=O)[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)[C@@]1([H])CC(C)=C(C)C(=O)O1
Molecular Formula
C28H38O5
Molecular Weight
454.6
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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