Ganoderic acid A

CAT: 0931-MF-0019025-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0019025-01Size:1 mg
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CAS Number
81907-62-2
Target
Autophagy|||Apoptosis|||NF-?B|||Endogenous Metabolite
Related Pathways
Autophagy|||Apoptosis|||NF-?B|||Metabolism
Purity
0.9984
Bioactivity
1. Ganoderic acid A exhibits antitumor activity, mediated through its inhibitory effect on nuclear transcription factor-kappaB and activator protein-1. 2. Ganoderic acid A can induce proliferation inhibition, apoptosis and suppression of invasion in human osteosarcoma HOS and MG-63 cells. 3. Ganoderic acid A promotes cisplatin-induced cell death by enhancing the sensitivity of HepG2 cells to cisplatin mainly via the signal transducer and activator of transcription 3 suppression, significantly suppresses IL-6-induced signal transducer and activator of transcription 3 phosphorylation.
Smiles
C[C@H](CC(=O)C[C@@H](C)C(O)=O)[C@H]1C[C@H](O)[C@@]2(C)C3=C(C(=O)C[C@]12C)[C@@]1(C)CCC(=O)C(C)(C)C1C[C@@H]3O
Molecular Formula
C30H44O7
Molecular Weight
516.67
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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