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Beta-Hydroxyisovalerylshikonin

CAT: 0931-TN1440-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-TN1440-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
7415-78-3
Target
Prostaglandin Receptor|||Fatty Acid Synthase|||AMPK|||EGFR|||Src|||Tyrosine Kinases
Related Pathways
Immunology/Inflammation|||PI3K/Akt/mTOR signaling|||Angiogenesis|||Tyrosine Kinase/Adaptors|||Chromatin/Epigenetic|||Metabolism|||JAK/STAT signaling|||GPCR/G Protein
Purity
0.9959
Bioactivity
Beta-Hydroxyisovalerylshikonin is an inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumor cell lines. Beta-Hydroxyisovalerylshikonin significantly decreased viability of HCT116 cells (IC50 values = 30.9 ?g/mL) .
Smiles
CC(C)=CC[C@@H](OC(=O)CC(C)(C)O)C1=CC(=O)c2c(O)ccc(O)c2C1=O
Molecular Formula
C21H24O7
Molecular Weight
388.41
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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