Beta-Hydroxyisovalerylshikonin

• Target:

  Prostaglandin Receptor|||Fatty Acid Synthase|||AMPK|||EGFR|||Src|||Tyrosine Kinases

• Related Pathways:

  Immunology/Inflammation|||PI3K/Akt/mTOR signaling|||Angiogenesis|||Tyrosine Kinase/Adaptors|||Chromatin/Epigenetic|||Metabolism|||JAK/STAT signaling|||GPCR/G Protein

• Purity:

  0.9959

• Bioactivity:

  Beta-Hydroxyisovalerylshikonin is an inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumor cell lines. Beta-Hydroxyisovalerylshikonin significantly decreased viability of HCT116 cells (IC50 values = 30.9 ?g/mL) .

• Smiles:

  CC (C) =CC[C@@H] (OC (=O) CC (C) (C) O) C1=CC (=O) c2c (O) ccc (O) c2C1=O

• Molecular Formula:

  C21H24O7

• Molecular Weight:

  388.41

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  7415-78-3