Arnicolide D

• Target:

  Apoptosis|||Caspase|||Akt|||NF-?B|||STAT|||mTOR|||ROS|||PI3K

• Related Pathways:

  JAK/STAT signaling|||NF-?B|||PI3K/Akt/mTOR signaling|||Cytoskeletal Signaling|||Apoptosis|||Proteases/Proteasome|||Stem Cells|||Immunology/Inflammation

• Purity:

  0.9993

• Bioactivity:

  Arnicolide D is a sesquiterpene lactone. Arnicolide D isolates from Centipeda minima. Arnicolide D modulates the cell cycle, activates the caspase signaling pathway and inhibits the PI3K/AKT/mTOR and STAT3 signaling pathways. Arnicolide D inhibits Nasopharyngeal carcinoma (NPC) cell viability in a concentration- and time-dependent manner. Arnicolide D exerts strong cytotoxic activity on the human colon carcinoma HT-29 cell line.

• Smiles:

  [H][C@@]12C[C@@H] (C) [C@]3 ([H]) C=CC (=O) [C@@]3 (C) [C@@H] (OC (=O) C (C) =C) [C@]1 ([H]) [C@H] (C) C (=O) O2

• Molecular Formula:

  C19H24O5

• Molecular Weight:

  332.39

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  34532-68-8