Arnicolide D

• Target :

  Apoptosis|||Caspase|||Akt|||NF-?B|||STAT|||mTOR|||ROS|||PI3K

• Related Pathways :

  JAK/STAT signaling|||NF-?B|||PI3K/Akt/mTOR signaling|||Cytoskeletal Signaling|||Apoptosis|||Proteases/Proteasome|||Stem Cells|||Immunology/Inflammation

• Purity :

  0.9993

• Bioactivity :

  Arnicolide D is a sesquiterpene lactone. Arnicolide D isolates from Centipeda minima. Arnicolide D modulates the cell cycle, activates the caspase signaling pathway and inhibits the PI3K/AKT/mTOR and STAT3 signaling pathways. Arnicolide D inhibits Nasopharyngeal carcinoma (NPC) cell viability in a concentration- and time-dependent manner. Arnicolide D exerts strong cytotoxic activity on the human colon carcinoma HT-29 cell line.

• Smiles :

  [H][C@@]12C[C@@H](C)[C@]3([H])C=CC(=O)[C@@]3(C)[C@@H](OC(=O)C(C)=C)[C@]1([H])[C@H](C)C(=O)O2

• Molecular Formula :

  C19H24O5

• Molecular Weight :

  332.39

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  34532-68-8