4'-Hydroxywogonin

• Target:

  ROS|||Interleukin|||PI3K|||MAPK|||Bcl-2 Family|||Akt|||NF-?B|||Caspase|||Apoptosis|||p38 MAPK|||Reactive Oxygen Species|||IL Receptor|||I?B/IKK|||TNF

• Related Pathways:

  Cytoskeletal Signaling|||NF-?B|||MAPK|||Metabolism|||Proteases/Proteasome|||PI3K/Akt/mTOR signaling|||Immunology/Inflammation|||Apoptosis

• Bioactivity:

  4'-Hydroxywogonin (8-Methoxyapigenin), a natural flavonoid with anti-inflammatory properties, reduced the production of pro-inflammatory cytokines (e.g., TNF-?, IL-6, and IL-1?), inhibited the TAK1/IKK/NF-?B signaling pathway, and reduced the phosphorylation of MAPKs and the PI3/Akt signaling pathway.

• Smiles:

  O=C1C=C(OC=2C(OC)=C(O)C=C(O)C12)C=3C=CC(O)=CC3

• Molecular Formula:

  C16H12O6

• Molecular Weight:

  300.26

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  57096-02-3