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(2S) -2'-Methoxykurarinone

CAT: 0931-TN1215-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-TN1215-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
270249-38-2
Target
RANKL/RANK, Akt, Antifection
Related Pathways
Cytoskeletal Signaling, Microbiology/Virology, NF-κB, PI3K/Akt/mTOR signaling
Purity
0.9944
Bioactivity
(2S) -2'-Methoxykurarinone is isolated from the roots of Sophora flavescens. (2S) -2'-Methoxykurarinone has anti-inflammatory, antipyretic, antidiabetic, and antineoplastic effects. (2S) -2'-Methoxykurarinone inhibits osteoclastogenesis and bone resorption through down-regulation of RANKL signaling. (2S) -2'-Methoxykurarinone displays cytotoxic activity against human myeloid leukemia HL-60 cells.
Smiles
COc1cc(O)ccc1[C@@H]1CC(=O)c2c(OC)cc(O)c(C[C@@H](CC=C(C)C)C(C)=C)c2O1
Molecular Formula
C27H32O6
Molecular Weight
452.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C