Products for Research Use Only
RegisterLogin

Lupanine

CAT: 0931-TMA0805-01Size: 100 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-TMA0805-01Size:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
550-90-3
Target
AChR, Potassium Channel, Beta Amyloid
Related Pathways
Membrane transporter/Ion channel, Neuroscience
Bioactivity
Lupanine ((+) -Lupanine), a naturally occurring quinolizidine alkaloid, potently affinity and activates nicotinic acetylcholine receptor (nAChR) (Ki=500 nM), and shows significant neuroprotection against soluble amyloid β-oligomers (SO-Aβ) toxicity in cellular models in association with the anti-apoptotic PI3K/ Akt/Bcl-2 signaling pathway with anti-Alzheimer's disease potential. Improves glucose homeostasis by affecting KATP channels and enhancing insulin secretion with therapeutic potential for type 2 diabetes.
Smiles
O=C1N2[C@@]([C@]3(C[C@@](C2)([C@]4(N(C3)CCCC4)[H])[H])[H])(CCC1)[H]
Molecular Formula
C15H24N2O
Molecular Weight
248.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Related Products

CatalogName
T32973Lupinine, (+) -
Fr16605-01Lupinine
Fr16605L-01Lupinine hydrochloride
T5708-01LUPENONE
T32974-01Lupinine, acrylate (ester)

Alternative Products

CatalogName
CS-BT-00422Lupanine
HY-N3359BLupanine (hydrochloride)
453972-01(+) -Lupanine Perchlorate
TRC-L474830-1MG(+)-Lupanine Perchlorate
MBS5782530Lupanine dihydrochloride, (+/-)-
BAA02539-01(+) -Lupanine hydrochloride
FL65068Lupanine perchlorate
MBS5817559Lupanine hydrochloride
HY-N3359ALupanine (perchlorate)
GTR19223330-01Lupanine dihydrochloride, (+/-) -

Popular Products