GLL 398

• Target:

  Estrogen Receptor/ERR

• Related Pathways:

  Endocrinology/Hormones

• Bioactivity:

  GLL 398 is an orally active and selective degrader of estrogen receptor with an IC50 of 1.14 nM. GLL 398 blocks tumor growth in xenograft breast cancer models.

• Smiles:

  CC/C(C1=CC=CC=C1)=C(C2=CC=C(B(O)O)C=C2)/C3=CC=C(C=C3)/C=C/C(O)=O

• Molecular Formula:

  C25H23BO4

• Molecular Weight:

  398.26

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2077980-80-2