MKC-1

• Target :

  Microtubule Associated|||Akt|||Apoptosis|||mTOR

• Related Pathways :

  Cytoskeletal Signaling|||Apoptosis|||PI3K/Akt/mTOR signaling

• Purity :

  0.9985

• Bioactivity :

  MKC-1 (Ro-31-7453) is an orally bioavailable small-molecule bisindolylmaleimide cell cycle inhibitor with potential antineoplastic activity. MKC-1 and its metabolites inhibit tubulin polymerization, blocking mitotic spindle formation, which may result in apoptosis and tumor cell death.

• Smiles :

  Cn1cc(C2=C(C(=O)NC2=O)c2cn(C)c3cc(ccc23)[N+]([O-])=O)c2ccccc12

• Molecular Formula :

  C22H16N4O4

• Molecular Weight :

  400.39

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  125313-92-0