VY-3-135

• Target :

  Others|||Acetyl-CoA Carboxylase|||Fatty Acid Synthase

• Related Pathways :

  Others|||Metabolism

• Purity :

  0.9979

• Bioactivity :

  VY-3-135 is an orally active, stable and specific acetyl-CoA synthetase 2 (ACSS2) inhibitor with IC50 of 44 nM, showing no inhibitory activity against recombinant human ACSS1 or ACSS3. VY-3-135 can effectively inhibit ACSS2-dependent fatty acid metabolism but has no effect on gene expression in tumors.

• Smiles :

  CCn1c(nc2ccc(cc12)C(=O)NC[C@@H](C)O)C(O)(c1ccccc1)c1ccccc1

• Molecular Formula :

  C26H27N3O3

• Molecular Weight :

  429.51

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1824637-41-3