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EST73502 hydrochloride

CAT: 0931-T9669-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T9669-01Size:2 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2307458-82-6
Target
Opioid Receptor, Others, Sigma receptor
Related Pathways
GPCR/G Protein, Neuroscience, Endocrinology/Hormones, Others
Bioactivity
EST73502 hydrochloride is a selective, orally active and blood-brain barrier (BBB) penetrant dual μ-opioid receptor (MOR) agonist and σ1 receptor (σ1R) antagonist, with K i s of 64 nM and 118 nM for MOR and σ1R, respectively. EST73502 hydrochloride has antinociceptive activity with reduced opioid-induced relevant adverse events[1].
Smiles
CCN1CC2(CCN(CCC3=CC(F)=CC=C3F)CC2)O[C@H](C)C1=O
Molecular Formula
C19H27ClF2N2O2
Molecular Weight
388.88
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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