MG-115

• Target:

  Proteasome|||Apoptosis

• Related Pathways:

  Apoptosis|||Ubiquitination|||Proteases/Proteasome

• Purity:

  0.9712

• Bioactivity:

  MG-115 (Z-LL-Nva-CHO) is a potent and reversible inhibitor of proteasome , with K i s of 21 nM and 35 nM for 20S and 26S proteasome, respectively. MG-115 specifically inhibit the chymotrypsin-like activity of the proteasome, induces p53-dependent apoptosis [1] [2] [3].

• Smiles:

  CCCC(NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)OCc1ccccc1)C=O

• Molecular Formula:

  C25H39N3O5

• Molecular Weight:

  461.59

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  133407-86-0