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CVN424

CAT: 0931-T9346-02Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T9346-02Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2254706-21-1
Target
GPCR
Related Pathways
Endocrinology/Hormones, GPCR/G Protein
Purity
0.9902
Bioactivity
CVN424 is a selective and novel GPR6 Inverse agonist effective in models of Parkinson Disease.
Smiles
CC(=O)N1CCc2nc(N3CCC(CC3)Oc3ccc(F)cc3F)c(N[C@@H]3CCOC3)nc2C1
Molecular Formula
C24H29F2N5O3
Molecular Weight
473.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

Cvn-424

CVN-424 is under investigation in clinical trial NCT06006247 (Early Parkinson's Disease Monotherapy With CVN424).

CAS Number2254706-21-1
PubChem CID137359492
IUPAC Name1-[2-[4-(2,4-difluorophenoxy)piperidin-1-yl]-3-[[(3R)-oxolan-3-yl]amino]-7,8-dihydro-5H-pyrido[3,4-b]pyrazin-6-yl]ethanone
Molecular FormulaC24H29F2N5O3
Molecular Weight473.5
XLogP2.4
Topological Polar Surface Area79.8
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count9
Rotatable Bond Count5
Heavy Atom Count34
Formal Charge0
Complexity698
SMILES
CC(=O)N1CCC2=C(C1)N=C(C(=N2)N3CCC(CC3)OC4=C(C=C(C=C4)F)F)N[C@@H]5CCOC5
InChI
InChI=1S/C24H29F2N5O3/c1-15(32)31-10-6-20-21(13-31)28-23(27-17-7-11-33-14-17)24(29-20)30-8-4-18(5-9-30)34-22-3-2-16(25)12-19(22)26/h2-3,12,17-18H,4-11,13-14H2,1H3,(H,27,28)/t17-/m1/s1
InChIKey
HSWVJQBEXRKOBZ-QGZVFWFLSA-N
Chemical Structure
2D Structure
2D structure of Cvn-424
CAS: 2254706-21-1
CID: 137359492
Formula: C24H29F2N5O3
MW: 473.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight473.5
XLogP32.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count9
Rotatable Bond Count5
Exact Mass473.22384613
Monoisotopic Mass473.22384613
Topological Polar Surface Area79.8 Ų
Heavy Atom Count34
Formal Charge0
Complexity698
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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