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CVN417

CAT: 0931-T78827-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T78827-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Others, AChR
Related Pathways
Others, Neuroscience
Bioactivity
CVN417 is an orally active antagonist of nAChR containing the α6 subunit, modulating phasic dopaminergic neurotransmission in an impulse-dependent fashion. It inhibits Ca (2+) efflux through nAChR subunits, displaying IC50 values of 0.086 μM (α6), 2.56 μM (α3), and 0.657 μM (α4) . CVN417 has shown efficacy in reducing resting tremor in rodent models, suggesting a potential to ameliorate movement disorders in conditions like Parkinson's disease [1].
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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