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KY19382

CAT: 0931-T9025-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T9025-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2226664-93-1
Target
GSK-3, Wnt/beta-catenin
Related Pathways
Cytoskeletal Signaling, Stem Cells, PI3K/Akt/mTOR signaling
Purity
0.9806
Bioactivity
KY19382 (2H-Indol-2-one, 5,6-dichloro-3-[1,3-dihydro-3- (methoxyimino) -2H-indol-2-ylidene]-1,3-dihydro-Ky19382) is a potent and orally active dual inhibitor of CXXC5-DVL and GSK3β (IC50s of 19 and 10 nM, respectively) . It activates Wnt/β-catenin signaling through inhibitory effects on both CXXC5-DVL interaction and GSK3β activity. KY19382 can be used for the research of high fat diet (HFD) induced metabolic diseases.
Smiles
CO\N=C1/C(/Nc2ccccc/12)=C1/C(=O)Nc2cc(Cl)c(Cl)cc12
Molecular Formula
C17H11Cl2N3O2
Molecular Weight
360.19
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
BA8690-5KY19382
C11601-25mgKY19382 (A3051)

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