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ICCB-19 hydrochloride

CAT: 0931-T8931L-01Size: 1 mL - 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0931-T8931L-01Size:1 mL - 10 mM (in DMSO)
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1803605-68-6
Target
Apoptosis, Autophagy, RIP kinase
Related Pathways
Apoptosis, Autophagy, NF-κB
Purity
0.993
Bioactivity
ICCB-19 hydrochloride (ICCB-19 HCl) is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain) . It binds to a pocket on the N-terminal TRAF2-binding domain of TRADD (TRADD-N), which interacts with the C-terminal domain (TRADD-C) and TRAF2 to modulate the ubiquitination of RIPK1 and beclin 1.
Smiles
Cl.O=C(CSC1=NCCN1)NC1CCCCCC1
Molecular Formula
C12H22ClN3OS
Molecular Weight
291.84
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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