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YUM70

CAT: 0931-T8901-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T8901-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
423145-35-1
Target
Apoptosis, HSP, GPCR
Related Pathways
Endocrinology/Hormones, Cytoskeletal Signaling, GPCR/G Protein, Metabolism, Apoptosis
Purity
0.9801
Bioactivity
YUM70 is a potent and selective inhibitor of glucose-regulated protein 78 (GRP78), with an IC50 of 1.5 μM for inhibiting GRP78 ATPase activity of the full-length protein. It induces endoplasmic reticulum (ER) stress-mediated apoptosis in pancreatic cancer.
Smiles
CCCC(=O)NC(c1ccc2OCOc2c1)c1cc(Cl)c2cccnc2c1O
Molecular Formula
C21H19ClN2O4
Molecular Weight
398.84
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

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BA2827-25YUM70
A22559-100YUM70 100mg
A22559-50YUM70 50mg
A22559-25YUM70 25mg
A22559-10YUM70 10mg
A22559-1YUM70 1mg
A22559-200YUM70 200mg
A22559-5YUM70 5mg
A22559-10mM-DYUM70 10mM * 1mL in DMSO

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