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NAE-IN-M22

CAT: 0931-T8816-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T8816-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
864420-54-2
Target
Apoptosis, E1/E2/E3 Enzyme
Related Pathways
Apoptosis, Ubiquitination
Purity
0.9867
Bioactivity
NAE-IN-M22 (NEDD8 inhibitor M22) is a selective, potent and reversible inhibitor of NEDD8 activating enzyme (NAE) . NAE-IN-M22 inhibits multiple cancer cell lines and induces apoptosis in A549 cells. NAE-IN-M22 also can inhibit tumor growth in vivo.
Smiles
Clc1ccc(CCNC2CCN(Cc3ccccc3)CC2)c(Cl)c1
Molecular Formula
C20H24Cl2N2
Molecular Weight
363.32
Shipping Conditions
Ice Packs
Storage Temperature
-20°C