MSA-2

• Target :

  STING

• Related Pathways :

  Immunology/Inflammation

• Purity :

  0.9888

• Bioactivity :

  MSA-2 is an orally available non-nucleotide STING agonist. The non-covalent dimer of MSA-2 binds to STING with nanomolar affinity. It shows anti-tumor activity in syngeneic mouse tumor models, synergizes with anti-PD-1, stimulates tumor secretion of interferon-?, induces tumor regression, and has long-lasting anti-tumor immunity. [3]

• Smiles :

  COc1cc2cc(sc2cc1OC)C(=O)CCC(O)=O

• Molecular Formula :

  C14H14O5S

• Molecular Weight :

  294.32

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  129425-81-6