MID-1

CAT: 0931-T8773-01Size: 1 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0931-T8773-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

312608-54-1

Target

IGF-1R

Related Pathways

Tyrosine Kinase/Adaptors

Purity

0.9961

Bioactivity

MID-1 is an inhibitor of MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) interaction. It disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skeletal muscle, leading to elevated IRS-1 expression level and increased insulin signaling and glucose uptake

Smiles

CCOc1ccc(cc1)C(=O)Nc1ncc(s1)[N+]([O-])=O

Molecular Formula

C12H11N3O4S

Molecular Weight

293.3

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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MID-1

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