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MAZ51

CAT: 0931-T8496-02Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T8496-02Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
163655-37-6
Target
VEGFR, Apoptosis
Related Pathways
Apoptosis, Angiogenesis, Tyrosine Kinase/Adaptors
Purity
0.9853
Bioactivity
MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.
Smiles
CN(C)c1ccc(\C=C2\C(=O)Nc3ccccc23)c2ccccc12
Molecular Formula
C21H18N2O
Molecular Weight
314.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

3-(4-Dimethylaminonaphthalen-1-ylmethylene)-1,3-dihydroindol-2-one
CAS Number163655-37-6
PubChem CID24906291
IUPAC Name3-[[4-(dimethylamino)naphthalen-1-yl]methylidene]-1H-indol-2-one
Molecular FormulaC21H18N2O
Molecular Weight314.4
XLogP4.3
Topological Polar Surface Area32.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count2
Heavy Atom Count24
Formal Charge0
Complexity512
SMILES
CN(C)C1=CC=C(C2=CC=CC=C21)C=C3C4=CC=CC=C4NC3=O
InChI
InChI=1S/C21H18N2O/c1-23(2)20-12-11-14(15-7-3-4-9-17(15)20)13-18-16-8-5-6-10-19(16)22-21(18)24/h3-13H,1-2H3,(H,22,24)
InChIKey
VFCXONOPGCDDBQ-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 3-(4-Dimethylaminonaphthalen-1-ylmethylene)-1,3-dihydroindol-2-one
CAS: 163655-37-6
CID: 24906291
Formula: C21H18N2O
MW: 314.4
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight314.4
XLogP34.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count2
Exact Mass314.141913202
Monoisotopic Mass314.141913202
Topological Polar Surface Area32.3 Ų
Heavy Atom Count24
Formal Charge0
Complexity512
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count1
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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