Products for Research Use Only

SR-4835

CAT: 0931-T8325-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T8325-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2387704-62-1
Target
Apoptosis, CDK
Related Pathways
Cell Cycle/Checkpoint, Apoptosis
Purity
>99.99%
Bioactivity
SR-4835 is a highly selective dual inhibitor of CDK12 and CDK13 (CDK12: IC50=99 nM, Kd=98 nM; CDK13: Kd=4.9 nM), which disables triple-negative breast cancer (TNBC) cells
Smiles
Cn1cc(cn1)-n1cnc2c(NCc3nc4cc(Cl)c(Cl)cc4[nH]3)nc(nc12)N1CCOCC1
Molecular Formula
C21H20Cl2N10O
Molecular Weight
499.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C