SR-4835

• Target:

  Apoptosis|||CDK

• Related Pathways:

  Cell Cycle/Checkpoint|||Apoptosis

• Purity:

  >99.99%

• Bioactivity:

  SR-4835 is a highly selective dual inhibitor of CDK12 and CDK13 (CDK12: IC50=99 nM, Kd=98 nM; CDK13: Kd=4.9 nM), which disables triple-negative breast cancer (TNBC) cells

• Smiles:

  Cn1cc(cn1)-n1cnc2c(NCc3nc4cc(Cl)c(Cl)cc4[nH]3)nc(nc12)N1CCOCC1

• Molecular Formula:

  C21H20Cl2N10O

• Molecular Weight:

  499.36

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2387704-62-1