(E/Z) -GSK5182

• Target :

  Reactive Oxygen Species|||Estrogen/progestogen Receptor|||Estrogen Receptor/ERR|||ROS

• Related Pathways :

  Metabolism|||Immunology/Inflammation|||NF-?B|||Endocrinology/Hormones

• Purity :

  0.9883

• Bioactivity :

  (E/Z) -GSK5182 (GSK5182 (Z/E) ) is a racemic mixture comprising (E) -GSK5182 and (Z) -GSK5182 isomers. It acts as a highly selective and orally active inverse agonist for the estrogen-related receptor ? (ERR?), demonstrating potency with an IC50 of 79 nM. Additionally, GSK5182 is known to induce the generation of reactive oxygen species (ROS) in hepatocellular carcinoma.

• Smiles :

  CN(C)CCOC1=CC=C(C=C1)C(=C(CCCO)C1=CC=CC=C1)C1=CC=C(O)C=C1

• Molecular Formula :

  C27H31NO3

• Molecular Weight :

  417.54

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2699724-40-6