(E/Z) -GSK5182

• Description:

  (E/Z) -GSK5182 (GSK5182 (Z/E) ) is a racemic mixture comprising (E) -GSK5182 and (Z) -GSK5182 isomers. It acts as a highly selective and orally active inverse agonist for the estrogen-related receptor γ (ERRγ), demonstrating potency with an IC50 of 79 nM. Additionally, GSK5182 is known to induce the generation of reactive oxygen species (ROS) in hepatocellular carcinoma.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  417.54

• Molecular Formula:

  C27H31NO3

• Notes:

  Research use only, not for human use.

• Receptor:

  ROS | Estrogen/progestogen Receptor

• CAS Number:

  2699724-40-6