(E/Z) -GSK5182

CAT: 1410-M36812-01Size: 1 gDry Ice: NoHazardous: No
CAT#:1410-M36812-01Size:1 g
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Description
(E/Z) -GSK5182 (GSK5182 (Z/E) ) is a racemic mixture comprising (E) -GSK5182 and (Z) -GSK5182 isomers. It acts as a highly selective and orally active inverse agonist for the estrogen-related receptor γ (ERRγ), demonstrating potency with an IC50 of 79 nM. Additionally, GSK5182 is known to induce the generation of reactive oxygen species (ROS) in hepatocellular carcinoma.
CAS Number
2699724-40-6
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
417.54
Molecular Formula
C27H31NO3
Notes
Research use only, not for human use.
Receptor
ROS | Estrogen/progestogen Receptor

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