PF 05089771

• Target :

  Sodium Channel

• Related Pathways :

  Membrane transporter/Ion channel

• Purity :

  0.9957

• Bioactivity :

  PF 05089771 is a Selective inhibitor of Nav1.7 (IC50 = 11 nM) that interacts with the voltage-sensor domain of domain IV. It shows a slow onset of the block that is depolarization and concentration-dependent.

• Smiles :

  Nc1n[nH]cc1-c1cc(Cl)ccc1Oc1cc(F)c(cc1Cl)S(=O)(=O)Nc1cscn1

• Molecular Formula :

  C18H12Cl2FN5O3S2

• Molecular Weight :

  500.35

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1235403-62-9