PF 05089771

• Target:

  Sodium Channel

• Related Pathways:

  Membrane transporter/Ion channel

• Purity:

  0.9957

• Bioactivity:

  PF 05089771 is a Selective inhibitor of Nav1.7 (IC50 = 11 nM) that interacts with the voltage-sensor domain of domain IV. It shows a slow onset of the block that is depolarization and concentration-dependent.

• Smiles:

  Nc1n[nH]cc1-c1cc (Cl) ccc1Oc1cc (F) c (cc1Cl) S (=O) (=O) Nc1cscn1

• Molecular Formula:

  C18H12Cl2FN5O3S2

• Molecular Weight:

  500.35

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1235403-62-9