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PF 05089771

CAT: 0931-T7502L-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0931-T7502L-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1235403-62-9
Target
Sodium Channel
Related Pathways
Membrane transporter/Ion channel
Purity
0.9957
Bioactivity
PF 05089771 is a Selective inhibitor of Nav1.7 (IC50 = 11 nM) that interacts with the voltage-sensor domain of domain IV. It shows a slow onset of the block that is depolarization and concentration-dependent.
Smiles
Nc1n[nH]cc1-c1cc(Cl)ccc1Oc1cc(F)c(cc1Cl)S(=O)(=O)Nc1cscn1
Molecular Formula
C18H12Cl2FN5O3S2
Molecular Weight
500.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C