2-Iminobiotin

• Target:

  NOS|||NO Synthase

• Related Pathways:

  Immunology/Inflammation

• Bioactivity:

  2-Iminobiotin (Guanidinobiotin) is a cyclic guanidino analog of biotin and serves as a reversible inhibitor of inducible nitric oxide synthase (iNOS) and neuronal NOS (nNOS), with Ki values of 21.8 ?M for mouse iNOS and 37.5 ?M for rat nNOS.

• Smiles:

  C (CCCC (O) =O) [C@H]1[C@@]2 ([C@@] (N=C (N) N2) (CS1) [H]) [H]

• Molecular Formula:

  C10H17N3O2S

• Molecular Weight:

  243.33

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  13395-35-2