PNU-74654

• Target:

  Apoptosis|||Wnt/beta-catenin

• Related Pathways:

  Stem Cells|||Apoptosis|||Cytoskeletal Signaling

• Purity:

  0.98

• Bioactivity:

  PNU 74654 binds to ?-catenin (Kd = 450 nM), inhibiting its interaction with the transcription factor T cell factor 4 (Tcf4) resulting in disruption of the Wnt signaling pathway.

• Smiles:

  Cc1ccc (\C=N\NC (=O) c2ccccc2Oc2ccccc2) o1

• Molecular Formula:

  C19H16N2O3

• Molecular Weight:

  320.34

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  113906-27-7