PNU-74654

• Target :

  Apoptosis|||Wnt/beta-catenin

• Related Pathways :

  Stem Cells|||Apoptosis|||Cytoskeletal Signaling

• Purity :

  0.98

• Bioactivity :

  PNU 74654 binds to ?-catenin (Kd = 450 nM), inhibiting its interaction with the transcription factor T cell factor 4 (Tcf4) resulting in disruption of the Wnt signaling pathway.

• Smiles :

  Cc1ccc(\C=N\NC(=O)c2ccccc2Oc2ccccc2)o1

• Molecular Formula :

  C19H16N2O3

• Molecular Weight :

  320.34

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  113906-27-7