PNU-145156E

• Target:

  VEGFR|||FGFR

• Related Pathways:

  Tyrosine Kinase/Adaptors|||Angiogenesis

• Bioactivity:

  PNU-145156E (formerly FCE 26644) is a noncytotoxic small molecule that exerts antitumor activity through reversible complex formation with growth and angiogenic factors, thereby inhibiting their ability to induce angiogenesis. PNU-145156E is utilized in research on tumor vascularization, angiogenesis regulation, and the development of anti-angiogenic therapeutic strategies.

• Smiles:

  O=C(NC=1C=C(C(=O)NC=2C=C(C(=O)NC3=CC=C4C=C(C=C(C4=C3)S(=O)(=O)O)S(=O)(=O)O)N(C2)C)N(C1)C)NC=5C=C(C(=O)NC=6C=C(C(=O)NC7=CC=C8C=C(C=C(C8=C7)S(=O)(=O)O)S(=O)(=O)O)N(C6)C)N(C5)C

• Molecular Formula:

  C45H40N10O17S4

• Molecular Weight:

  1121.12

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  159537-58-3