Products for Research Use Only
RegisterLogin

Tenofovir Disoproxil

CAT: 0931-T7111-01Size: 1 mL - 10 mM (in DMSO)Dry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T7111-01Size:1 mL - 10 mM (in DMSO)
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
201341-05-1
Target
Reverse Transcriptase, HIV Protease, HBV
Related Pathways
Proteases/Proteasome, Microbiology/Virology
Purity
0.9917
Bioactivity
Tenofovir Disoproxil (GS 4331) is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B.
Smiles
C([C@H](OCP(OCOC(OC(C)C)=O)(OCOC(OC(C)C)=O)=O)C)N1C=2C(N=C1)=C(N)N=CN2
Molecular Formula
C19H30N5O10P
Molecular Weight
519.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

Tenofovir Disoproxil

Tenofovir disoproxil is an organic phosphonate that is the disoproxil ester of tenofovir. A prodrug for tenofovir, an HIV-1 reverse transcriptase inhibitor, tenofovir disoproxil is used as the fumaric acid salt in combination therapy for the treatment of HIV infection. It has a role as an antiviral drug, a prodrug and a HIV-1 reverse transcriptase inhibitor. It is functionally related to a tenofovir (anhydrous).

CAS Number201341-05-1
PubChem CID5481350
IUPAC Name[[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-(propan-2-yloxycarbonyloxymethoxy)phosphoryl]oxymethyl propan-2-yl carbonate
Molecular FormulaC19H30N5O10P
Molecular Weight519.4
XLogP1.6
Topological Polar Surface Area185
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count14
Rotatable Bond Count17
Heavy Atom Count35
Formal Charge0
Complexity698
SMILES
C[C@H](CN1C=NC2=C(N=CN=C21)N)OCP(=O)(OCOC(=O)OC(C)C)OCOC(=O)OC(C)C
InChI
InChI=1S/C19H30N5O10P/c1-12(2)33-18(25)28-9-31-35(27,32-10-29-19(26)34-13(3)4)11-30-14(5)6-24-8-23-15-16(20)21-7-22-17(15)24/h7-8,12-14H,6,9-11H2,1-5H3,(H2,20,21,22)/t14-/m1/s1
InChIKey
JFVZFKDSXNQEJW-CQSZACIVSA-N
Chemical Structure
2D Structure
2D structure of Tenofovir Disoproxil
CAS: 201341-05-1
CID: 5481350
Formula: C19H30N5O10P
MW: 519.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight519.4
XLogP31.6
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count14
Rotatable Bond Count17
Exact Mass519.17302917
Monoisotopic Mass519.17302917
Topological Polar Surface Area185 Ų
Heavy Atom Count35
Formal Charge0
Complexity698
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
T1649-01Tenofovir
T21775-01Tenofovir maleate
T1649L-01Tenofovir hydrate
T37909-01Tenofovir diphosphate
T39043-01Tenofovir amibufenamide
T2409-01Tenofovir alafenamide
T28946-01Tenofovir exalidex
T12814-01(S) -Tenofovir
T37909L-01Tenofovir diphosphate TEA
T41249-01Tenofovir alafenamide fumarate

Alternative Products

CatalogName
XGC28415-01Tenofovir disoproxil
RM-T140629-01Tenofovir Disoproxil Impurity 3 (6N-Hydroxymethyl Tenofovir Disoproxil)
HY-115430Tenofovir disoproxil aspartate
289955-01Tenofovir disoproxil isopropoxycarbonyl
1920-5Tenofovir disoproxil fumarate
RM-T140601-01Tenofovir Disoproxil Impurity A
TRC-T018515-50MGTenofovir Disoproxil Dimer

Popular Products