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VR23

CAT: 0931-T7016-01Size: 1 mL - 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0931-T7016-01Size:1 mL - 10 mM (in DMSO)
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1624602-30-7
Target
Proteasome, Apoptosis, Caspase
Related Pathways
Apoptosis, Ubiquitination, Proteases/Proteasome
Purity
0.9962
Bioactivity
VR23 is a potent proteasome inhibitor. Data shows IC50 =1 nM for trypsin-like proteasomes, IC50=50-100 nM for chymotrypsin-like proteasomes, and IC50=3 μM for caspase-like proteasomes.
Smiles
[O-][N+](=O)c1ccc(c(c1)[N+]([O-])=O)S(=O)(=O)N1CCN(CC1)c1ccnc2cc(Cl)ccc12
Molecular Formula
C19H16ClN5O6S
Molecular Weight
477.88
Shipping Conditions
Ice Packs
Storage Temperature
-20°C