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Nardosinone

CAT: 0931-T6S1740-04Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T6S1740-04Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
23720-80-1
Target
Others
Related Pathways
Others
Purity
0.99
Bioactivity
1. Nardosinone has inhibitory effect on Ang II-induced hypertrophy in H9c2 cells, might be mediated by targeting PI3K/Akt and MEK/ERK signaling pathways. 2. Nardosinone could protect against the neuronal injury exposed to OGD, which may be relevant to the promotion of PKA and ERK signaling pathway. 3. Nardosinone enhances staurosporine- or dbcAMP-induced neurite outgrowth from PC12D cells, probably by amplifying both the MAP kinase-dependent and -independent signaling pathways of dbcAMP and staurosporine. 4. The enhancement of NGF-induced neurite outgrowth from PC12D cells by Nardosinone involves activation of a down-stream step of the MAP kinase-dependent cascade of NGF coupled with PKC.
Smiles
C[C@@H]1CCC=C2C(=O)C[C@H]3OOC(C)(C)[C@H]3[C@@]12C
Molecular Formula
C15H22O3
Molecular Weight
250.33
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

Nardosinone

Nardosinone has been reported in Nardostachys jatamansi with data available.

CAS Number23720-80-1
PubChem CID168136
IUPAC Name(3aR,9R,9aR,9bS)-1,1,9,9a-tetramethyl-3a,4,7,8,9,9b-hexahydronaphtho[2,1-c]dioxol-5-one
Molecular FormulaC15H22O3
Molecular Weight250.33
XLogP2.9
Topological Polar Surface Area35.5
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count0
Heavy Atom Count18
Formal Charge0
Complexity423
SMILES
C[C@@H]1CCC=C2[C@]1([C@H]3[C@@H](CC2=O)OOC3(C)C)C
InChI
InChI=1S/C15H22O3/c1-9-6-5-7-10-11(16)8-12-13(15(9,10)4)14(2,3)18-17-12/h7,9,12-13H,5-6,8H2,1-4H3/t9-,12-,13+,15+/m1/s1
InChIKey
KXGHHSIMRWPVQM-JWFUOXDNSA-N
Chemical Structure
2D Structure
2D structure of Nardosinone
CAS: 23720-80-1
CID: 168136
Formula: C15H22O3
MW: 250.33
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight250.33
XLogP32.9
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count0
Exact Mass250.15689456
Monoisotopic Mass250.15689456
Topological Polar Surface Area35.5 Ų
Heavy Atom Count18
Formal Charge0
Complexity423
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
TB0397-0020Nardosinone
A14691-50Nardosinone 50mg
A14691-2Nardosinone 2mg
HY-N0380RNardosinone (Standard)

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