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Nardosinone

CAT: 0931-T6S1740-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T6S1740-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
23720-80-1
Target
Others
Related Pathways
Others
Purity
0.99
Bioactivity
1. Nardosinone has inhibitory effect on Ang II-induced hypertrophy in H9c2 cells, might be mediated by targeting PI3K/Akt and MEK/ERK signaling pathways. 2. Nardosinone could protect against the neuronal injury exposed to OGD, which may be relevant to the promotion of PKA and ERK signaling pathway. 3. Nardosinone enhances staurosporine- or dbcAMP-induced neurite outgrowth from PC12D cells, probably by amplifying both the MAP kinase-dependent and -independent signaling pathways of dbcAMP and staurosporine. 4. The enhancement of NGF-induced neurite outgrowth from PC12D cells by Nardosinone involves activation of a down-stream step of the MAP kinase-dependent cascade of NGF coupled with PKC.
Smiles
C[C@@H]1CCC=C2C(=O)C[C@H]3OOC(C)(C)[C@H]3[C@@]12C
Molecular Formula
C15H22O3
Molecular Weight
250.33
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
TB0397-0020Nardosinone
A14691-50Nardosinone 50mg
A14691-2Nardosinone 2mg
HY-N0380RNardosinone (Standard)
A14691-5Nardosinone 5mg

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