Linarin

CAT: 0931-T6S0653-04Size: 25 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0931-T6S0653-04Size:25 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

CAS Number

480-36-4

Target

PKA, Apoptosis, Cholinesterase (ChE), HIV Protease, Influenza Virus, Antibacterial, TNF

Related Pathways

Proteases/Proteasome, Tyrosine Kinase/Adaptors, Neuroscience, Microbiology/Virology, Apoptosis

Purity

0.9899

Bioactivity

1. Linarin (Acacetin-7-O-rutinoside) (acacetin-7-O-β-d-rutinoside) shows selective dose dependent inhibitory effect on acetylcholinesterase. 2. Linarin alleviates GalN/LPS-induced liver injury by suppressing TNF-α-mediated apoptotic pathways. 3. Linarin prevents A beta-induced neurotoxicity through the activation of PI3K/Akt, which subsequently inhibits GSK-3b and up-regulates Bcl-2. 4. The piperine significantly enhanced the oral absorption of Linarin in rats by inhibiting P-glycoprotein mediated cellular efflux during the intestinal absorption and likely simultaneously by inhibiting the metabolism of Linarin.

Smiles

COc1ccc(cc1)-c1cc(=O)c2c(O)cc(OC3OC(COC4OC(C)C(O)C(O)C4O)C(O)C(O)C3O)cc2o1

Molecular Formula

C28H32O14

Molecular Weight

592.55

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

Linarin

linarin has been reported in Silene firma, Pinus sylvestris, and other organisms with data available.

CAS Number	480-36-4
PubChem CID	5317025
IUPAC Name	5-hydroxy-2-(4-methoxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one
Molecular Formula	C28H32O14
Molecular Weight	592.5
XLogP	-0.5
Topological Polar Surface Area	214
Hydrogen Bond Donor Count	7
Hydrogen Bond Acceptor Count	14
Rotatable Bond Count	7
Heavy Atom Count	42
Formal Charge	0
Complexity	955

SMILES

C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)OC3=CC(=C4C(=C3)OC(=CC4=O)C5=CC=C(C=C5)OC)O)O)O)O)O)O)O

InChI

InChI=1S/C28H32O14/c1-11-21(31)23(33)25(35)27(39-11)38-10-19-22(32)24(34)26(36)28(42-19)40-14-7-15(29)20-16(30)9-17(41-18(20)8-14)12-3-5-13(37-2)6-4-12/h3-9,11,19,21-29,31-36H,10H2,1-2H3/t11-,19+,21-,22+,23+,24-,25+,26+,27+,28+/m0/s1

InChIKey

YFVGIJBUXMQFOF-PJOVQGMDSA-N

Chemical Structure

2D Structure

CAS: 480-36-4

CID: 5317025

Formula: C28H32O14

MW: 592.5

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	592.5
XLogP3	-0.5
Hydrogen Bond Donor Count	7
Hydrogen Bond Acceptor Count	14
Rotatable Bond Count	7
Exact Mass	592.17920569
Monoisotopic Mass	592.17920569
Topological Polar Surface Area	214 Å²
Heavy Atom Count	42
Formal Charge	0
Complexity	955
Isotope Atom Count	0
Defined Atom Stereocenter Count	10
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

Catalog	Name
T32765	Lineatin
T32771-01	Linuron
T25731-01	Linatine
T19648-01	Linamarin
T32772	Linuron-trifluralin mixt
TSW-00463-01	2,3,4,6-Tetra-O-acetyl linamarin

Alternative Products

Catalog	Name
SM2029-10mM	Linarin
HY-N0528R-01	Linarin (Standard)
300567	Linarin (Buddleoside)
371648	Linarin discontinued
GTR19179354	Linarin 4'''-acetate
AR-D01917-01	Diosmin EP Impurity E (Linarin)

Linarin

Chemical Information

Related Products

Alternative Products

Popular Products