Linarin

• Target:

  PKA|||Apoptosis|||Cholinesterase (ChE) |||HIV Protease|||Influenza Virus|||Antibacterial|||TNF

• Related Pathways:

  Proteases/Proteasome|||Tyrosine Kinase/Adaptors|||Neuroscience|||Microbiology/Virology|||Apoptosis

• Purity:

  0.9899

• Bioactivity:

  1. Linarin (Acacetin-7-O-rutinoside) (acacetin-7-O-?-d-rutinoside) shows selective dose dependent inhibitory effect on acetylcholinesterase. 2. Linarin alleviates GalN/LPS-induced liver injury by suppressing TNF-?-mediated apoptotic pathways. 3. Linarin prevents A beta-induced neurotoxicity through the activation of PI3K/Akt, which subsequently inhibits GSK-3b and up-regulates Bcl-2. 4. The piperine significantly enhanced the oral absorption of Linarin in rats by inhibiting P-glycoprotein mediated cellular efflux during the intestinal absorption and likely simultaneously by inhibiting the metabolism of Linarin.

• Smiles:

  COc1ccc (cc1) -c1cc (=O) c2c (O) cc (OC3OC (COC4OC (C) C (O) C (O) C4O) C (O) C (O) C3O) cc2o1

• Molecular Formula:

  C28H32O14

• Molecular Weight:

  592.55

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  480-36-4