Linarin

• Target :

  PKA|||Apoptosis|||Cholinesterase (ChE) |||HIV Protease|||Influenza Virus|||Antibacterial|||TNF

• Related Pathways :

  Proteases/Proteasome|||Tyrosine Kinase/Adaptors|||Neuroscience|||Microbiology/Virology|||Apoptosis

• Purity :

  0.9899

• Bioactivity :

  1. Linarin (Acacetin-7-O-rutinoside) (acacetin-7-O-?-d-rutinoside) shows selective dose dependent inhibitory effect on acetylcholinesterase. 2. Linarin alleviates GalN/LPS-induced liver injury by suppressing TNF-?-mediated apoptotic pathways. 3. Linarin prevents A beta-induced neurotoxicity through the activation of PI3K/Akt, which subsequently inhibits GSK-3b and up-regulates Bcl-2. 4. The piperine significantly enhanced the oral absorption of Linarin in rats by inhibiting P-glycoprotein mediated cellular efflux during the intestinal absorption and likely simultaneously by inhibiting the metabolism of Linarin.

• Smiles :

  COc1ccc(cc1)-c1cc(=O)c2c(O)cc(OC3OC(COC4OC(C)C(O)C(O)C4O)C(O)C(O)C3O)cc2o1

• Molecular Formula :

  C28H32O14

• Molecular Weight :

  592.55

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  480-36-4