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Olmutinib

CAT: 0931-T6918-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T6918-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1353550-13-6
Target
EGFR, BTK
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis, JAK/STAT signaling
Purity
0.9963
Bioactivity
Olmutinib (HM61713, BI 1482694) is an orally available small molecule, a mutant-selective inhibitor of epidermal growth factor receptor (EGFR) with potential antineoplastic activity. Olmutinib binds to and inhibits mutant forms of EGFR, thereby leading to cell death of EGFR-expressing tumor cells. As this agent is selective towards mutant forms of EGFR, its toxicity profile may be reduced as compared to non-selective EGFR inhibitors which also inhibit the EGFR wild-type form.
Smiles
CN1CCN(CC1)c1ccc(Nc2nc(Oc3cccc(NC(=O)C=C)c3)c3sccc3n2)cc1
Molecular Formula
C26H26N6O2S
Molecular Weight
486.59
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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