Olmutinib

• CAS Number :

  1353550-13-6

• Target :

  EGFR|||BTK

• Related Pathways :

  Tyrosine Kinase/Adaptors|||Angiogenesis|||JAK/STAT signaling

• Purity :

  0.9963

• Bioactivity :

  Olmutinib (HM61713, BI 1482694) is an orally available small molecule, a mutant-selective inhibitor of epidermal growth factor receptor (EGFR) with potential antineoplastic activity. Olmutinib binds to and inhibits mutant forms of EGFR, thereby leading to cell death of EGFR-expressing tumor cells. As this agent is selective towards mutant forms of EGFR, its toxicity profile may be reduced as compared to non-selective EGFR inhibitors which also inhibit the EGFR wild-type form.

• Smiles :

  CN1CCN(CC1)c1ccc(Nc2nc(Oc3cccc(NC(=O)C=C)c3)c3sccc3n2)cc1

• Molecular Formula :

  C26H26N6O2S

• Molecular Weight :

  486.59

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C