Halofuginone

• Target:

  TGF-beta/Smad|||Sodium Channel|||DNA/RNA Synthesis|||Calcium Channel|||Parasite

• Related Pathways:

  Microbiology/Virology|||Membrane transporter/Ion channel|||Metabolism|||DNA Damage/DNA Repair|||Cell Cycle/Checkpoint|||Stem Cells

• Purity:

  0.9953

• Bioactivity:

  Halofuginone (RU-19110), the competitive inhibitor of prolyl-tRNA synthetase (Ki=18.3 nM), could also down-regulate Smad3 and blocked TGF-? signaling at 10 ng/ml in the mammal.

• Smiles:

  O[C@@H]1CCCN[C@H]1CC(=O)Cn1cnc2cc(Br)c(Cl)cc2c1=O

• Molecular Formula:

  C16H17BrClN3O3

• Molecular Weight:

  414.68

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  55837-20-2