Bitopertin

• Target:

  GlyT

• Related Pathways:

  Neuroscience

• Purity:

  >99.99%

• Bioactivity:

  Bitopertin (Paliflutine) (RG1678, RO-4917838) is a potent inhibitor of glycine transporter 1 (GlyT1), with Ki of 8.1 nM for human hGlyT1b and IC50 of 22-25 nM in Chinese hamster ovary cells.

• Smiles:

  C[C@H](Oc1ccc(cc1C(=O)N1CCN(CC1)c1ncc(cc1F)C(F)(F)F)S(C)(=O)=O)C(F)(F)F

• Molecular Formula:

  C21H20F7N3O4S

• Molecular Weight:

  543.46

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  845614-11-1