Bitopertin (Standard)

CAT: 0804-HY-10809R-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-10809R-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Bitopertin (Standard) is the analytical standard of Bitopertin. This product is intended for research and analytical applications. Bitopertin is a potent, noncompetitive glycine reuptake inhibitor, inhibits glycine uptake at human GlyT1 with a concentration exhibiting IC50 of 25 nM.
CAS Number
[845614-11-1]
UNSPSC
12352100
Target
GlyT; Reference Standards
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling; Others
Field of Research
Neurological Disease
Smiles
FC1=CC(C(F)(F)F)=CN=C1N2CCN(C(C3=CC(S(=O)(C)=O)=CC=C3O[C@H](C(F)(F)F)C)=O)CC2
Molecular Formula
C21H20F7N3O4S
Molecular Weight
543.46
References & Citations
[1]Alberati D, et al. Glycine reuptake inhibitor RG1678: A pharmacologic characterization of an investigational agent for the treatment of schizophrenia. Neuropharmacology. 2012 Feb;62 (2) :1152-61.|[2]Pinard E, et al. Selective GlyT1 Inhibitors: Discovery of [4- (3-Fluoro-5-trifluoromethylpyridin-2-yl) piperazin-1-yl][5-methanesulfonyl-2- ((S) -2,2,2-trifluoro-1-methylethoxy) phenyl]methanone (RG1678), a Promising Novel Medicine To Treat Schizophrenia. J Me
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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