Bitopertin (Standard)

• Description :

  Bitopertin (Standard) is the analytical standard of Bitopertin. This product is intended for research and analytical applications. Bitopertin is a potent, noncompetitive glycine reuptake inhibitor, inhibits glycine uptake at human GlyT1 with a concentration exhibiting IC50 of 25 nM.

• UNSPSC :

  12352100

• Target :

  GlyT; Reference Standards

• Related Pathways :

  Membrane Transporter/Ion Channel; Neuronal Signaling; Others

• Field of Research :

  Neurological Disease

• Smiles :

  FC1=CC(C(F)(F)F)=CN=C1N2CCN(C(C3=CC(S(=O)(C)=O)=CC=C3O[C@H](C(F)(F)F)C)=O)CC2

• Molecular Formula :

  C21H20F7N3O4S

• Molecular Weight :

  543.46

• References & Citations :

  [1]Alberati D, et al. Glycine reuptake inhibitor RG1678: A pharmacologic characterization of an investigational agent for the treatment of schizophrenia. Neuropharmacology. 2012 Feb;62 (2) :1152-61.|[2]Pinard E, et al. Selective GlyT1 Inhibitors: Discovery of [4- (3-Fluoro-5-trifluoromethylpyridin-2-yl) piperazin-1-yl][5-methanesulfonyl-2- ((S) -2,2,2-trifluoro-1-methylethoxy) phenyl]methanone (RG1678), a Promising Novel Medicine To Treat Schizophrenia. J Me

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference Standards

• CAS Number :

  [845614-11-1]